
PhD-Developed, Patent-Pending Butyrate
Trusted by 200+ U.S. Clinicians & Physicians
(452 reviews)




Developed with advanced research methods
Most digestive issues after 45 stem from depleted butyrate – the fuel that powers 70% of colon cells. Our PXRcap™ Technology is the first to deliver this critical nutrient past stomach acid directly to your colon.
“I noticed a difference in my bowel movements within 3 days of starting Tributyrin X. And now I am able to eat vegetables, beans, nuts, and bread without having excess gas and bloating. And, my bowel movements are more regular and normal consistency. I have always had bouts of constipation, bloating, and gas; and now I feel so free.”

“This Tributyrin-X works wonders my digestive system is finally cleared my metabolism and immune system is better than ever I breathe better I have lost a few pounds because of Tributyrin-X I am a new person it’s wonderful.”

“I’ve been having problems with acid stomach and constipation that has gotten worse over the last year. I’ve tried several things that have helped a little but this product fixed it. I can’t tell you how grateful I am for that.”

“I had severe diarrhea for 4 months with unknown causes. I tried Fodmap diet for 5 weeks with no results. I added 3 different probiotics with still no change. Once I added Tributyrin, my diarrhea was gone by the sixth day and I am back to normal!!”

Using patent-pending, clinically proven technology, Tributyrin-X™ delivers 99.9% pure butyrate directly to your colon, targeting the true root cause, so you can finally stop the frustrating cycle of digestive remedies that never quite work.*

Up to 70% of your colon cells rely on butyrate for energy — it’s the fuel that keeps your digestive muscles moving and inflammation low. But during menopause, butyrate levels often drop, which slows down motility, weakens the muscles that push food through, and leaves the gut sensitive. That’s when you start seeing constipation, sudden urgency, or bloating that seems to come out of nowhere.
Tributyrin-X™ delivers pure butyrate directly to your colon — addressing the root cause that probiotics, prebiotics, and diet changes try but often fail to fix. It recharges the cells that keep digestion moving, reduces pressure and gas buildup, and helps restore a smoother, more predictable rhythm to your gut.*

When butyrate drops during menopause, the gut barrier weakens and your microbiome becomes less diverse. That means food particles can leak through and trigger immune reactions — leading to bloating, pain, or digestive flare-ups after eating foods you once tolerated with no issue.*
Tributyrin-X™ helps reseal the gut lining and support the regrowth of beneficial bacteria — reducing food sensitivities, calming inflammation, and helping your gut stay more stable, tolerant, and healthy over time.*


Butyrate helps stimulate GLP-1 — a gut hormone that curbs appetite, improves blood sugar balance, and supports fat metabolism. When butyrate drops, cravings can spike and fat becomes harder to lose, especially around the midsection.*
It also supports Prevotella, a beneficial gut bacteria linked to easier weight loss and better blood sugar balance. In one study, people with more Prevotella lost up to 18 pounds more fat on the same diet.* This was featured in the Netflix documentary Hack Your Health, where researchers found that women lacking Prevotella struggled to lose weight — even when eating healthy.*

Tributyrin-X™ doesn’t just deliver butyrate. It helps create the environment your gut needs to start making it again — restoring stronger digestion, a sealed barrier, and a more diverse, self-sufficient microbiome.*
Some studies show probiotics can be up to 100x more effective in the right gut environment.* After all, probiotics are just good bacteria — but without butyrate, they can’t survive or do their job. By restoring butyrate, you help your own beneficial bacteria thrive — so digestion runs smoothly, bloating fades, and your gut can finally take care of itself.*

“I do not think these products treat symptoms, instead, it is my observation that they are really altering the gut terrain”

“The science and research behind these products give me the confidence in prescribing them to my patients”

“I’ve been working in the gut microbiome field for a long time and their products have been a complete game changer”

Tributyrin-X™ is the first supplement to combine two breakthroughs in menopausal gut health: The purest, most bioavailable form of butyrate on the market, and patented PXRcap™ technology, clinically proven for targeted delivery that meets pharmaceutical standards.

Hey, it’s the founders Steven and Jordan here.
When Jordan and I started this journey, we weren’t looking to create just another gut supplement. This was personal for us.

Jordan’s mother passed away unexpectedly at just 52 years old. It was devastating. As we looked back, we realized she had spent her entire life battling gut problems — things like constipation, stomach pain, fatigue, and chronic headaches.
She relied on medication and endless treatments, but never found lasting relief. Her health deteriorated, and ultimately, it cost her her life. Jordan later faced similar problems, dealing with erratic bowel movements and fatigue, leading him to fear for his future and not seeing his daughter down the aisle at her wedding. And not being around to hold his grandkids.
For me, my struggles were different but equally draining. Bloating, fatigue, weight gain — I tried countless products but nothing worked. That’s when Jordan and I decided to dig into the science and find a real solution.
We discovered that butyrate could be the key to healing our guts. We tried over forty different butyrate products on the market, but we were shocked at the inconsistency and poor performance. We couldn’t figure out why they weren’t working.

ABOVE: Steven & Jordan on Sacagawea Peak, Montana. Neither of us having to ONCE think about where the nearest bathroom was.
That’s when we partnered with a PhD chemist from Spain, who had spent years researching gut health. Together, we figured it out: it wasn’t just about supplementing with butyrate, it was about delivering it the right way. After extensive research, we developed a patented delivery system to get pure, bioavailable butyrate directly to the colon, where it’s needed most.
And that’s how Tributyrin-X™ was born.
Since then, we’ve dedicated ourselves to helping others, educating people through over 30 million views on our gut health content.
Thousands of women experiencing the challenges of menopause have found real relief with Tributyrin-X™. We’re so confident it will work for you that we offer a 60-Day Guarantee. If it doesn’t change your life, we’ll refund you, even if the bottle is empty. We created this to help women like you, and we’re proud to stand behind it.
Here’s to better health,
Steven & Jordan
Combine purity with precision. Backed by 15+ years of gut research, our patented capsule delivers 99.9% pure butyrate directly to the colon — where it works fast, without odor, leaks, or side effects.



Tributyrin-X™ was formulated with over 15 years of experience in gut health research. Created by Steven Wright, a Functional Medicine Engineer, it’s the result of a relentless quest to find the most powerful and effective butyrate formula available. Working alongside one of the world’s top butyrate scientists, Steven crafted Tributyrin-X™ to deliver maximum potency and bioavailability.

Tributyrin-X™ is manufactured in GMP-certified facilities, adhering to the strictest safety and quality standards. Every batch undergoes rigorous quality control to ensure it meets our high standards for purity, potency, and safety.

Unlike other butyrate supplements that are often diluted or mixed with less effective compounds, Tributyrin-X™ contains 99.9% pure liquid tributyrin. This means your gut receives the most potent and bioavailable form of butyrate without any unnecessary fillers.

Our patent-pending PXRcap™ Softgel Technology is a breakthrough in butyrate delivery. It ensures that the butyrate survives stomach acid and reaches your intestines intact. In fact, PXRcap™ studies show zero capsule leakage after two hours in simulated gastric acid, and complete dissolution within just 2.15 minutes once in the intestines. This guarantees maximum absorption and effectiveness—solving the biggest problem with traditional butyrate supplements.

We take quality seriously. Tributyrin-X™ is non-GMO, gluten-free, dairy-free, soy-free, and contains zero fillers, preservatives, or artificial additives. You’re getting nothing but pure, powerful butyrate in each capsule.

We believe in our product, and so do thousands of satisfied customers. That’s why we offer a 60-day money-back guarantee. Try Tributyrin-X™ risk-free, and if you’re not completely satisfied, we’ll refund your purchase without hassle.

With 500+ 5-star reviews and over 3 million pills sold, customers trust Tributyrin-X™ to support their digestive health, energy levels, and overall wellness. It’s a life-changing solution for those dealing with gut discomfort, food sensitivities, or unpredictable digestion.
Tributyrin-X™ is for anyone looking for gut health support, inflammation support, immune system support, digestive comfort, metabolic support, over-eating support, and microbiome support.
It’s been our experience that you might notice results within days of starting Tributyrin-X™. If your body needs a higher dose you’ll know it when you get there. This may include less digestive pains, less bloating, easier bowel movements every morning like clockwork, improvements in inflammation-related issues, fewer cravings or less desire to eat as much food, the ability to tolerate more foods in the diet, and more…
Some studies show that beneficial effects of butyrate still get stronger even after 12 weeks of usage.
Other human studies of 1 year of usage showed users who stayed consistent and took it regularly had higher quality of life scores compared to placebo and less digestive upset relapses.
So, there appears to be an additive benefit to regularly taking butyrate-containing supplements week-by-week, month-by-month.
You can! However, it’s unlikely that you get enough butyrate from your food sources to be physiologically beneficial, making butyrate supplementation a better option for gaining significant health benefits.
Butyrate can also be made in the gut by consuming resistant starch, which typically comes from the skins of legumes or underripe bananas—foods that aren’t commonly consumed.
Additionally, if you’re already experiencing symptoms of gut dysfunction—like diarrhea, constipation, bloating, or food sensitivities—it may be a sign that your butyrate-producing bacteria have declined, especially as you age. When beneficial bacteria are compromised, digestion isn’t optimal, and adding more fiber can actually backfire, feeding harmful bacteria instead.
That’s why supplementing with butyrate first is essential to establish a strong gut environment and robust barrier. Once your gut is fortified and balanced, it can better support natural butyrate production on its own, allowing fiber to work as intended.
We are unable to guarantee today’s special offer beyond midnight today. Once word gets out about our Best Deal, there’ll be a mad rush. Supplies are limited and once it’s gone, so is this special deal.
No, butyrate is NOT bacteria but a short-chain fatty acid (SCFA). It’s produced in the lower colon by beneficial bacteria breaking down fiber and then taken up by colonocytes, the cells that line the colon. Butyrate becomes an essential fuel source for these cells, helping to maintain a healthy, oxygen-free environment that supports good bacteria.
However, as we age, the bacteria that produce butyrate naturally decline, often due to lifestyle factors, stress, or even antibiotic use. This can lead to an insufficient supply of butyrate, compromising gut health and leaving the colon more vulnerable. That’s why supplementing with butyrate can be crucial, especially when the gut environment is already compromised or aging has depleted beneficial bacterial populations.
No. Tributyrin-X™ does NOT contain Gluten, Dairy, Soy, Zero Sugar, and is GMO free.
When you order, you will instantly receive an order confirmation email. You can relax then because we are working hard to get your order out the door to you as quickly as possible!
We will ship your order directly to your home or office using a premium mail carrier, and you will have it within 5 to 10 business days of placing your order.
Products are shipped from Chicago IL, USA and we will send you a shipment notification email with tracking number as soon as your order ships so that you can track it right to your door.
We are confident that Tributyrin-X™ will work for you, and we stand behind that with a 60-Day Money-Back Guarantee. If you don’t see the results you’re hoping for—whether that’s smoother digestion, less bloating, more regular bowel movements, or just feeling lighter and more comfortable—we’ll make it right.
It doesn’t matter if you’ve used the entire bottle or just a few capsules—if you’re not satisfied for any reason, just reach out to our support team. We’ll process your refund, no questions asked. Even if the container is empty, you’ll still get your money back.
Your satisfaction and health are our top priorities, and we would never stand in the way of you getting healthier. We take the risk so you don’t have to. Try Tributyrin-X™ with complete peace of mind, knowing your purchase is completely protected.
Tributyrin-X™ is formulated to be safe for long-term use and is generally well-tolerated. As with any supplement, some people may experience mild digestive adjustments in the first few days as the gut microbiome rebalances. If you have any medical conditions or are taking medication, please consult your doctor before use.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.