
Gut Health > Menopause and Estrogen Loss
Advertorial Written by Mary Smith | Published on January 15, 2026
Names changed for privacy. Based on real experiences.

Hi, I’m Mary, and I’m about to tell you why I started collecting my own urine.
I know how that sounds. But when my friend Sarah (she’s a registered nurse) showed me what was happening every time I used the bathroom, everything about my three years of digestive misery suddenly made perfect sense.
You see, I’d become one of those women who could go for 5 days without pooping, even to the point I was scared of what would happen.
Foods like dairy, fried foods, steaks, and pastas made me bloated and gassy. I had to restrict my diet and it was just taking a toll – I loved food, I hated living in restriction because of the embarrassment that followed eating trigger foods.
What I didn’t know was that menopause was making me pee out something Harvard says is needed to activate digestion.
It wasn’t until Sarah had me do a simple test at home that I understood this cruel trick affecting 90% of menopausal women – and discovered the 7-second empty stomach method that now lets me eat all my trigger foods with zero issues, poop daily like clockwork, AND finally get the nutrition that was making me look and feel old.

Sarah had me bring a morning urine sample. She dipped a mineral test strip in it, and within seconds it lit up like a rainbow.
She explained I was peeing out hundreds of milligrams of digestive minerals daily. French researchers at Joseph Fourier University found postmenopausal women lose 35% more minerals than younger women through urine.
Then she showed me a strip from her younger patient – barely any color. That woman kept her minerals. I was flushing mine away.
I learned that kidneys are the most estrogen-responsive organ in your body after your reproductive system. When estrogen drops during menopause, kidneys stop holding onto minerals properly. They just let them flow right through, regardless of your diet.
The worst part? Harvard proved digestive enzymes are useless without these minerals. They’re like a car without a key – completely dead.
So my food just sat there undigested, fermenting like garbage in a hot dumpster, creating gas, constipation, and bloating.
But even worse – I wasn’t absorbing any of the nutrients that give me energy, keep my skin young, or make my hair thick.

That’s when Sarah revealed something that changed everything – a condition called “Gastropause.”
Just like menopause shuts down your reproductive system, Gastropause shuts down your digestion.
Your enzyme production drops by 50% while you simultaneously pee out 35% of the minerals needed to activate them.
But here’s what really blew my mind:
When your body realizes you only have 30% digestive power, it doesn’t just give up. It goes into full survival mode.
Think about it – what would happen if you couldn’t extract nutrients from food? You’d starve to death even with a full stomach.
So your body does something brilliant but brutal – it literally PAUSES your entire digestive system. When it detects you don’t have enough working enzymes, it slams the emergency brake. Stomach emptying grinds to a halt. Your intestines practically stop moving. Everything freezes.
Why? Your body is compensating. It’s thinking, “If I only have 30% enzyme power, I need to slow everything down by 70% to give those few working enzymes enough time.” It’s basic survival math – if you can’t increase digestive power, you increase digestive TIME.
Food that should pass in hours now rots for DAYS. The average woman with Gastropause has meals from 3 days ago still sitting in her stomach.

This explained why everything I’d tried had failed. Fiber supplements just added more bulk to an already paused system. Probiotics couldn’t colonize a gut where food was rotting instead of moving. Laxatives forced some waste out but did nothing to fix the enzyme crisis.
Even expensive digestive enzymes were useless – without minerals to activate them, they were as dead as the ones my body was struggling to produce. I’d spent $600 treating symptoms while Gastropause got progressively worse.

Steven Wright, the health engineer who discovered the mineral-enzyme connection, didn’t start out as a digestive health expert. His journey began when his business partner’s tragedy became his mission.
“My business partner Jordan and I met in college,” Steven explains. “But in 2005, Jordan’s mother unexpectedly died at just 52 years old.”
Looking back, they recognized a disturbing pattern: chronic bloating, severe constipation, and debilitating digestive pain that mainstream doctors consistently dismissed as “normal aging” or “just stress.”
“For years, she’d been prescribed medications that only masked symptoms without addressing the root cause,” Steven says. “No one connected the dots between her digestive problems and her rapidly declining health.”
This personal crisis led Steven and Jordan to befriend and eventually hire some of the brightest minds in digestive health, including Dr. Robert Brown, a brilliant PhD biochemist from Sandy, Utah who had been researching enzyme activation for years.
“We were determined to find answers that conventional medicine had missed,” Steven explains. “Through our connections with leading researchers like Dr. Brown, we discovered the critical link between digestive enzymes and specific minerals – the very minerals that women in menopause lose through increased urination.”
The partnership with Dr. Brown proved to be the turning point. Together, they developed a revolutionary approach that addresses both sides of the digestive problem simultaneously – enzyme production AND mineral activation.
⭐️⭐️⭐️⭐️⭐️ Rated 4.7/5 from 600+ Reviews

“HoloZyme is the most
activated enzyme in the world.”
“I’ve long been a fan of digestive enzymes. They not only address GI complaints; they also facilitate absorption of key nutrients. But in the past, quality has been hit or miss. Now, HoloZyme is the only digestive enzyme that marries the specific enzyme strain and perfect mineral cofactor that, together, create the most activated enzyme in the world.”
Dr. Ronald Hoffman
M.D., Albert Einstein College of Medicine
The result of Steven’s partnership with the PhD biochemist isn’t just another digestive supplement – it’s a revolutionary patented technology that solves the invisible mineral crisis happening in menopausal women’s bodies.*
Unlike every other enzyme formula on the market, HoloZyme™ doesn’t just assume your body has the minerals needed to “switch on” its enzymes. It delivers each enzyme pre-paired with its exact activating mineral cofactor in a proprietary ratio that ensures immediate action – even when your estrogen-depleted body is flushing these critical minerals away.*
What makes HoloZyme™ completely unique:
✅ AES® Patented Activation Technology – The only enzyme system awarded an official US Government patent for its mineral-enzyme pairing method*
✅ Activ-Blend™ Dual-Strain Enzymes – Works throughout your entire digestive tract regardless of pH level*
✅ 100% Activated Spectrum Coverage – Breaks down proteins, fats, carbohydrates, fiber, dairy, and legumes*
✅ 235mg Specific Mineral Activation Matrix – Contains 5X the mineral activators of competing products*

Official Patent Document for Holozyme’s
Patented Mineral Activation Technology
To secure their US Government patent, the team had to prove their formula was not just different but substantially more effective than anything else available.
Six rigorous human pilot studies costing over $250,000 demonstrated what thousands of women now know firsthand: HoloZyme™ succeeds where other enzyme supplements consistently fail.




Clinical studies showed HoloZyme™ helps restore your body’s ability to actually absorb and use nutrients from food – something Gastropause had stolen from you.
But what does that mean for your daily life?
First, the digestive relief you desperately need: You’ll poop daily again – no more sitting on the toilet for 20 minutes straining. The bloating disappears so you can button your pants all day. You can eat whatever you want without embarrassing gas or running to the bathroom.
But here’s the beautiful bonus of finally absorbing nutrients:
Your energy comes roaring back because you’re actually getting B vitamins and iron from your food. That bone-deep exhaustion lifts when your cells finally get fuel. Your skin starts glowing again as antioxidants reach your cells. Hair gets thicker because you’re absorbing proteins and minerals. Even your mood stabilizes – 90% of serotonin is made in a properly functioning gut.
Remember, you’ve been operating on 30% nutrient absorption. Imagine what happens when that jumps back to near 100%. It’s like the difference between trying to run a marathon on an empty tank versus a full one.
One woman told me, “I came for the constipation relief but stayed because I feel 20 years younger.” Another said, “My hairdresser asked what I was doing differently – my hair was growing faster and thicker than she’d seen in years.”
This is why HoloZyme™ isn’t just another digestive aid. When you reverse Gastropause and restore full digestive power, you’re not just fixing your gut – you’re unlocking all the nutrition that’s been trapped in your food. For the first time in years, you’re actually feeding your body instead of just filling your stomach.
⭐️⭐️⭐️⭐️⭐️ Rated 4.7/5 from 600+ Reviews

The most compelling proof comes from clinical validation and professional endorsements. HoloZyme™ has been through six human pilot studies and is recommended by over 200 health practitioners across the United States.*
“I do not think these products treat symptoms, instead, it is my observation that they are really altering the gut terrain.”
Mary F. Shackelton, MPH, NDT
“The science and research behind these products give me the confidence in prescribing them to my patients.”
Jessica Muniz, MSN, FNP-C
“I’ve been working in the gut microbiome field for a long time and their products have been a complete game changer.”
Haroldo Magarinos, ND, DDS
⭐️⭐️⭐️⭐️⭐️ Rated 4.7/5 from 600+ Reviews

If you’re tired of planning your life around unpredictable digestive issues…
If you’re frustrated with temporary solutions that only mask symptoms…
If you want to address the true causes of menopausal digestive distress once and for all…
Then it’s time to try the patented HoloZyme™ formula developed with a PhD biochemist specifically for women over 45.
Remember, you have absolutely nothing to risk.
Your purchase is backed by the same iron-clad 60-day “Bottom of the Bottle” guarantee that thousands of women have already trusted.
Plus, with today’s exclusive 30% discount, you’re getting the absolute best price available. That means you can use the entire bottle, even if it’s completely empty, and still get 100% of your money back if you’re not thrilled with your results for ANY reason.
No questions asked. No complicated return procedures. No “partial” refunds. Just a simple, complete refund if you’re not completely satisfied.
This confidence comes from seeing HoloZyme™ work for thousands of women just like you – even those who’ve tried everything else without success.
Important: Due to the specialized manufacturing process and this article going viral on social media, inventory is extremely limited. The last batch was unavailable for nearly 8 weeks after selling out, leaving thousands without access to relief. We’re already seeing 10x normal order volume since this report was published.
Rated 4.7/5 from 600+ Reviews
Still wondering if HoloZyme™ could really work for you when so many other solutions have failed? Just listen to these women who experienced relief starting as early as their first meal:

“This product is incredible!!! I have suffered from chronic bloating for over a decade, and no supplement, diet, or cleanse has helped. THIS, however, cleared it up within a month! I feel SO much better and am so grateful for everything about this product. I hope this supplement finds those who need it, like I did!”
emma, 53

“I wish I would have known about this product years ago. I had no idea my gas and bloating was because of low digestive enzymes. I first heard about HoloZyme from a podcast I normally listen to. After the podcaster gave it rave reviews, I decided to give it a try, and it’s the best thing I ever did. Best digestive enzyme on the market!”
Shirley, 47

“I was recommended HoloZyme by a family member who swore that this was the only thing that helped them digest their food. Ever since I’ve taken HoloZyme, I too now have less bloating and I’m able to eat the foods I love.”
Paula, 63
⭐️⭐️⭐️⭐️⭐️ Rated 4.7/5 from 600+ Reviews
From what I’ve seen in the thousands of reviews, it’s perfect for women like us going through perimenopause, menopause, or post-menopause. That’s when our enzyme production tanks and we start peeing out all our minerals. If you’re dealing with the bloating, constipation, and food sensitivities that hit after 45, this is for you.
I felt better with my very first meal – and reading the reviews, that’s pretty common. Most women notice less bloating within days. I was shocked when I ate a sandwich without consequences for the first time in years. Many reviewers say they could finally eat dairy or bread again within the first week.
This was the biggest “aha moment” for me. Sarah explained that regular enzyme supplements assume your body has minerals to activate them. But here’s the problem – when estrogen drops during menopause, we lose massive amounts of minerals through our urine. So those $600 worth of enzymes I bought? They were useless because I had no minerals to “turn them on.”
Dr. Ronald Hoffman from Albert Einstein College of Medicine explained it perfectly: “I’ve long been a fan of digestive enzymes… But in the past, quality has been hit or miss. Now, HoloZyme is the only digestive enzyme that marries the specific enzyme strain and perfect mineral cofactor that, together, create the most activated enzyme in the world.”
That’s exactly what I experienced – all those other enzymes were “miss” for me because they needed minerals I didn’t have.
HoloZyme™ comes with each enzyme pre-paired with its specific mineral. It’s like buying a flashlight with batteries already installed versus one that assumes you have batteries at home.
Yes, it costs more than basic enzymes – but they spent over $250,000 on human studies to perfect this patented formula. When you break it down, it’s less than a cup of coffee per day. After wasting hundreds on enzymes that didn’t work, paying a little more for something that actually freed me from bloating, constipation, and food fears? Best money I ever spent. I can finally poop daily and eat whatever I want – you can’t put a price on that.
From what I’ve seen, their deals don’t last long. When I ordered, they were running a similar promotion and it ended within days. Once word gets out, these special prices disappear fast.
No, that’s not how it works. I’ve been taking HoloZyme™ for months and my body still produces enzymes – this just supplements what menopause stole from us. I’ve noticed I can actually use less on some days when I’m feeling good, and more when I know I’m eating trigger foods.
Yes! It’s vegan, non-GMO, and free from gluten, dairy, soy, and eggs. No artificial junk either. Perfect for those of us who’ve developed sensitivities.
Mine came from Chicago and took about a week to reach me. They sent tracking info right away which was nice – I was anxiously waiting!
This gave me the confidence to try it – you get 60 days to test it completely risk-free. Even if you finish the entire bottle and aren’t happy, they’ll refund you. No hassles, no questions. That’s how confident they are it’ll work for you. The bottle is also super big so you can basically try it with 30 different foods if you want to.
It’s designed for digestion, but I noticed my energy came back and I started sleeping better once my gut wasn’t constantly inflamed. Many reviewers mention the same thing – when you’re actually absorbing nutrients and not dealing with constant bloating, everything improves.
They recommend 2 capsules with each meal, but I’ve learned to adjust based on what I’m eating. Big meals or trigger foods? Definitely 2. Something lighter? Either one or none. You’ll figure out what works for you.
⭐️⭐️⭐️⭐️⭐️ Rated 4.7/5 from 600+ Reviews

SUPPORT@HEALTHYGUT.COM | PHONE: (888) 612-5997
PAYMENTS WE ACCEPT:




Statements made within this website have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Please consult your healthcare professional before use if you are pregnant, breastfeeding, or considering use for a child. For more information please contact support@healthygutcom.bigscoots-staging.com
Copyright © 2025 Healthy Gut Company · All Rights Reserved